Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK) is a posterior corneal transplantation technique that replaces dysfunctional recipient endothelium with healthy donor tissue while sparing the entire recipient stroma.  DSAEK is currently recognized as the “state-of-the-art” in the endothelial keratoplasty field.

Dr. Melles first described the surgical technique for posterior lamellar keratoplasty, in 1998.  Then in 2001, Dr. Terry adopted this technique in the United States and renamed the procedure DLEK (Deep Lamellar Endothelial Keratoplasty).  In 2004, Dr. Melles described a technique in which he simply stripped Descemet’s membrane from the recipient and thus convert.

Descemets’ Stripping Automated Endothelial Keratoplasty (DSAEK) for Fuchs’ and other endothelial dystrophies (i.e. posterior polymorphous dystrophy), post-cataract surgery edema (aphakic or pseudophakic bullous keratopathy) and some of failed PK.

Superficial Anterior Lamellar Keratoplasty (SALK) indicated in the treatment of superficial corneal opacities resulting from previous refractive surgical procedures, infections, degenerations, dystrophies, superficial scars or trauma.

Deep Anterior Lamellar Keratoplasty (DALK) indicated when a thicker stromal lamella should be removed: keratoconus, post-herpetic scars, post-infectious opacities, some corneal dystrophies, and alkali or acid burn lesions.

Mushroom and Lap joint Keratoplasty indicated in patients with full-thickness central stromal opacities but normal endothelium.

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