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For the Relief of Severe Chronic Dry Eye Disease & Lagophthalmos Symptoms

I-DEFENCE® is a long-lasting, lubricating ointment that delivers superior moisturizing and protection of the ocular surface.

Containing 0.40% sodium hyaluronate, I-DEFENCE®’s formulation is extremely effective at providing maximum, long-lasting relief of dry eye symptoms and is well tolerated by the patient.

The unique viscous properties of I-DEFENCE® enable a prolonged contact-time with the ocular surface. This hydrating ointment provides soothing relief of dry eye symptoms, such as soreness, irritation or a gritty sensation on the eyes and acts as a barrier against moisture loss. It can be used during surgical procedures and is ideal for patients that suffer from nocturnal lagophthalmos.

I-DEFENCE® is recommended for night-time use. Upon application, the patient may experience a foreign body sensation that will pass after several blinks. If used during the day, it is recommended that the patient does not drive a car or operate heavy machinery, as their vision may be blurry due to the consistency of the ointment. I-DEFENCE® is most effective when used at night while the patient is asleep, which allows the ointment to remain on the cornea longer.

Do not use I-DEFENCE® with contact lenses.


Hydrating & Lubricating Dry Eye Ointment

Maximum Relief

For Severe Chronic Dry Eye

  • ✔ Contains 0.40% sodium hyaluronate
  • ✔ Enables a prolonged contact-time with the ocular surface
  • ✔ Immediate, long-lasting hydration and lubrication
  • ✔ Reduces tear film evaporation

Do not use with contact lenses

Format size: 5 g (0.18 fl. oz) tube

I-DEFENCE® comes in a sterile tube. In order to keep the tip of the tube and the contents sterile, it is recommended that I-DEFENCE® be dropped into the eye, without touching the cornea or surrounding tissues.

I-DEFENCE® should be used within eight weeks of opening.


  1. Wash your hands well before you use I-DEFENCE®
  2. When initially opening I-DEFENCE®, do not use the first delivery of the ointment, which may be aqueous. Gently squeeze the tube until the ointment begins to come out.
  3. Tilt your head up slightly and pull the lower eyelid downwards, to form a pouch.
  4. Hold the tube vertical to your eye.
  5. Press the tube gently to release a small quantity of the product on your eye (preferably at night). Repeat this process for your other eye.
  6. If an additional daily dose is required, apply a small quantity of the ointment to your eyes every three to four hours, or according to your doctor’s instructions.
  7. Please ensure that the tip of the tube does not touch anything, including your eye or your fingers.
  8. Close the cap tightly after use.

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