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Scientific Studies

I-LID ’N LASH® PLUS: A safe and effective product in managing demodicosis in vivo

To prove the efficacy of I-LID ’N LASH® PLUS containing 5% tea tree oil in managing Demodicosis by reducing the collarettes/cylindrical dandruff counts and improving tear film stability.

To prove the safety of 5% tea tree oil on the Meibomian glands, in vivo.

Authors: Shaun MacInnis O.D., Aleem Bandali O.D., Karim Fahmy Ph.D., Mahmoud Rammal Ph.D., Ilan Hofmann Ph.D.

Evaluating Viscosity and Tear Breakup Time of Contemporary Commercial Ocular Lubricants on an In Vitro Eye Model

To evaluate the link between the viscosity of ophthalmic formulation and tear film stability using a novel in vitro eye model.

Authors: Chau-Minh Phan; Mitchell Ross; Karim Fahmy; Blair McEwen; Ilan Hofmann; Vivian W. Y. Chan; Connor Clark-Baba; Lyndon Jones

Evaluation of the clinical effectiveness of Protectorial® isotonic eye ointment

Study examining 10 clinical cases of patients with dry eye disease who were treated with Protectorial® (marketed in Europe as Protectorial® and sold as I-DEFENCE® in Canada) isotonic eye ointment containing 0.4% sodium hyaluronate.

Authors: Domenico Porfi do, Elizaveta Pozharitskaya

Examining Symptomatic Relief and Kinetic Tear Film Stability of I-DROP® MGD Eye Drops

Authors: Alison Ng, Jaya Dantam, Jill Woods, Blair McEwen, Lyndon Jones

Role Of Rheology In Tears & Artificial Tears

Authors: A. Arshinoff, Steve MD, FRCSC; Hofmann, Ilan PhD; Nae, Hemi PhD

Rheological Behavior Of Commercial Artificial Tear Solutions

Authors: Arshinoff, Steve MD; Hofmann, Ilan PhD; Nae, Hemi PhD

Preliminary Report: Temperature Loss Profile for I-RELIEFTM Mask

Clinical Trial on E>EYE with IRPL® Technology

Trial Conducted by Dr. Shaun MacInnis on the effectiveness of E>EYE with IRPL® technology for MGD management.

Clinical Study on Blepharitis Patients Using I-LID ’N LASH® PLUS

Study Conducted by Dr. Steven D’Orio showing positive results for blepharitis patients using I-LID ’N LASH® PLUS.

Strip meniscometry tube: a rapid method for assessing aqueous deficient dry eye

Authors: Saleh Alshammeri*† MSc Louise Madden* PhD Suzanne Hagan* PhD E Ian Pearce* PhD

Economic burden and loss of quality of life from dry eye disease in Canada

Authors: Clara Chan, Setareh Ziai, Varun Myageri, James G Burns, C Lisa Prokopich

Effectiveness of sodium hyaluronate eye gel in patients with dry eye disease: A multi-centre, open label, uncontrolled study

Authors: Nasir Saeed1, ZA Qazi2, Nadeem H Butt3, Ahson Siddiqi4, Neeta Maheshwary5, Muhammad Athar Khan6

Understanding the Science Behind the Inflammatory Cascade of Dry Eye Disease

Authors: Lisa M Nijm1,2 and Grace E Dunbar2

Revisiting the vicious circle of dry eye disease: a focus on the pathophysiology of meibomian gland dysfunction

Authors: Christophe Baudouin,1,2 Elisabeth M Messmer,3 Pasquale Aragona,4 Gerd Geerling,5 Yonca A Akova,6 José Benítez-del-Castillo,7 Kostas G Boboridis,8 Jesús Merayo-Lloves,9 Maurizio Rolando,10 Marc Labetoulle11

Impressions of the I-PEN® Osmolarity System

Authors: Jessica MacIsaac Published: 21/04/2018 issue of OPTICIAN UK

An algorithm for the preoperative diagnosis and treatment of ocular surface disorders

Authors: Christopher E. Starr, MD, Preeya K. Gupta, MD, Marjan Farid, MD, Kenneth A. Beckman, MD, Clara C. Chan, MD, FRCSC, Elizabeth Yeu, MD, Jose A.P. Gomes, MD, PhD, Brandon D. Ayers, MD, John P. Berdahl, MD, Edward J. Holland, MD, Teny Kim, MD, Francis S. Mah, MD, the ASCRS Cornea Clinical Committee

A Randomized Multicenter Study Comparing 0.1%, 0.15%, and 0.3% Sodium Hyaluronate with 0.05% Cyclosporine in the Treatment of Dry Eye

Authors: Yuli Park,1 Jong Suk Song,2 Chul Young Choi,3 Kyung Chul Yoon,4 Hyung Keun Lee,5 and Hyun Seung Kim1

Novel Device Provides Rapid Measure of Tear Osmolarity

Ophthalmology Times Ophthalmology Dry eye
By Nancy Groves
Reviewed by Henry Reis, MD, OD

In Vivo Ocular Surface Osmolarity in a Dry Eye Population

Richard L. Maharaj, OD, FAAO
Clinical Director, eyeLABS Optometry and Center for Ocular Surface Disease
Associate Clinical Adjunct Faculty, University of Waterloo School of Optometry

Performance of an In Vivo Tear Film Osmometer in Normal Ocular Surface Conditions

Henry Reis, MD; Stefanie Grenier, BSc; Daniela Albuquerque, MD

Preliminary clinical study on the efficacy of propolis/aloe vera/chamomile compounded natural eye drops*

Claudio Peruccio
Ophthalmology Referrals, Turin Veterinary Centre, Torino, Italy

Dry Eye Disease Diagnosis and Management

Richard L. Maharaj, OD, FAAO

Tear Osmolarity: A Clinical Tool for the Diagnosis and Management of OSD

Dr François Piuze O.D.

Maintained concentration: Bill Harvey tries out the I-PEN® osmolarity system a useful addition to clinical practice

Author: Bill Harvey
Published: 01/06/2018 issue of OPTICIAN UK

A Comparison of In Vivo and In Vitro Osmometers for the Assessment of Dry Eye Disease

Henry Reis, MD; Stefanie Grenier, BSc; Daniela Albuquerque, MD
Clinical & Refractive Optometry Volume 28, Number 2, 2017

Validity and Reliability of a Novel Handheld Osmolarity System for Measurement of a National Institute of Standards Traceable Solution

Clara C. Chan, MD, FRCSC, FACS,* Armand Borovik, MBBS, FRANZCO,† Ilan Hofmann, PhD,‡ Eric Gulliver, BSc (Hons),§ and Guillermo Rocha, MD, FRCSC, FACS